Patients with Reduced orfenadrina ou carisoprodol carisoprodol for benzo withdrawal carisoprodol vs vicodin carisoprodol CYP2C19 Activity: SOMA should be used with caution in patients with reduced CYP2C19 activity .
Published studies indicate that patients who are poor CYP2C19 soma metabolizers have a 4-fold increase in exposure to carisoprodol, and concomitant 50% reduced exposure to meprobamate compared to normal CYP2C19 metabolizers .
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